All of the ESRs recruited by PET3D will be exposed to a variety of highly complementary research environments spanning different therapeutic areas: oncology, cardiovascular, neuroscience and all of the ESRs will spend at least one secondment in a different country and will have the opportunity to attend training events and consortium meetings in all of the 7 countries involved in PET3D.
Each ESR will be exposed to the following:
- Cutting edge research training, technical training, generic skills training.
- Cross-sectorial training – translational skills training, commercialisation.
- Access to state of the art technologies in each of the beneficiary sites.
- Transferrable and generic skills training – communications, presentation, writing, management, dissemination, intellectual property rights protection, dissemination and exploitation, ethical issues, entrepreneurial initiatives, CV writing and interview training available locally at each beneficiary site.
- Strong collaborative bonds with each ESR, with supervisors and mentors and also with researchers in related fields, thereby laying the foundation for future continued European-wide research collaboration.
ESR1 - Host ABD
AZ, month 12, for 6 months,
For in vitro and ex-vivo profiling, and pharmacokinetic studies on 3H/14C versions of fatty acid analogues and CPT1 inhibitors.
ESR2 - Host ABD
AMS, month 30, for 3 months,
‘for exploring full antibody or nanobody versions of the tracer.
ESR3 - Host AMS
1. BER, month 9, for 3 months,
for design and synthesis of target compounds.
2. IMA, month 18, for 6 months,
for performing chemistry and animal studies, development of complementary skills (e.g. business, project management).
ESR4 - Host AMD
1. ABD, month 26, for 6 months,
for evaluation of clearing agent on in vivo behaviour proteins and peptides.
2. BRU, month 33, for 2 months,
for comparing BRU’s nanobody technology products to come to best practice.
ESR5 - Host BRU
1. ABD, month 7, for 4 months
to gain knowledge on 18F-FDR radiochemistry
2. IMA, month 24, for 6 months,
for GMP production, toxicity study, IMPD writing, training on IP.
ESR6 - Host BRU
AZ, month 22, for 6 months,
translational pre-clinical studies on radioisotope- and NIR-labelled nanobodies.
ESR7 - Host SAN
1. ABD, month 14, for 6 months,
to gain knowledge on pre-targeting strategies and related synthetic chemistry.
2. IMA, month 35, for 4 months,
to acquire skills in image quantification and kinetic modeling.
ESR8 - Host SAN
1. BRU, month 16, for 2 months,
to gain knowledge on nanobody technology.
2. AZ, month 28, for 6 months,
to bind an oncology compound from AstraZeneca to the NanoBite platform.
ESR9 - Host BER
AZ, month 18, for 6 months,
for biodistribution studies through micro-dosing and drug validation studies.
ESR10 - Host BER
IMA, month 29, for 6 months
for performing biodistribution studies and metabolite characterisation.
ESR11 - Host MUN
IMA, month 12, for 6 months
to study therapeutic modulation of neuroinflammation via pre-clinical PET imaging.
ESR12 - Host MUN
AZ, month 6, for 6 months
to study best modality of therapeutic intervention (e.g. anti-angiogenesis).
ESR13 - Host ABD
AMS, month 24, for 6 months
for performing PET imaging studies on pre-targeted click tracers.
ESR14 - Host IMA
1. BER, month 13, for 3 months
for studying a pre-targeted approach to hypoxia PET imaging.
2. MUN, month 25, for 3 months
for exploring a pre-targeted PET imaging approach to gliomas.
3. ICL, month 8 and month 20 for 2 months each
characterisation of the constructs.
ESR15 - Host AZ
ABD, Month 18, for 6 months
to develop a [18F]-labeled tracer and perform pre-clinical studies in vivo.
In addition to local training, this ETN offers cutting-edge Network-wide training opportunities, see overview in ‘Main Network Training Events & Conferences’.
Dissemination events are public conferences or symposia on:
- hot scientific topics of interest to PET3D
- transferrable skills/employability workshops
- business-related events
These events will be of particular interest to radiopharmaceuticals/drug discovery stakeholders and students.
Schools are larger and structured training initiatives lasting from 2 days to 5 days.
Training events are smaller, 1-day training courses/workshops, which will be open to external participants and therefore will also represent dissemination opportunities.